| 特發性間質性肺炎 Idiopathic interstitial pneumonia | |
|---|---|
 | |
| Micrograph of usual interstitial pneumonia (UIP). UIP is the most common pattern of idiopathic interstitial pneumonia and usually represents 特发性肺纤维化. 苏木精-伊红染色. 驗屍 specimen. | |
| 症状 | 肺炎 |
| 类型 | 肺炎, 間質性肺病, 特發性, disease of a particular individual[*] |
| 分类和外部资源 | |
| 醫學專科 | 胸腔醫學 |
| ICD-11 | CB03 |
| Orphanet | 98300 |
特發性間質肺炎（Idiopathic interstitial pneumonia，簡稱IIP），又稱非感染性肺炎（noninfectious pneumonia），屬於一種間質性肺病。該疾病通常侵襲肺間質，有些也會侵襲氣道（例如Cryptogenic organizing pneumonitis），IIP可分為七個亞型。
組織學分類
IIP的分類相當複雜，須結合臨床觀察、影像學，以及病理学才能確診。
| 組織學 | 臨床相關意義 |
|---|---|
| Desquamative interstitial pneumonia (DIP) | DIP |
| Diffuse alveolar damage (DAD) | 急性呼吸窘迫症候群、急性間質性肺炎、輸血相關急性肺損傷 |
| 非特異性間質性肺炎（NSIP） | NSIP |
| Respiratory bronchiolitis | 呼吸性細支氣管相關之間質性肺病（RB-ILD） |
| 尋常性間質性肺炎 (UIP) | 自體免疫性疾病、特发性肺纤维化、致死量、肺塵病 |
| Organizing pneumonia | 隱源性機化性肺炎 |
| 淋巴樣間質性肺炎 (LIP) | LIP |
其中尋常性間質性肺炎為最常見的一種亞型。
發育
Table 1: Development of the (histologic) idiopathic interstitial pneumonia classification
| Leibow et al. (1969) | Katzenstein (1998) | ATS/ERS (2002) | |||||||||||||||||||||||||||
| UIP | UIP | ||||||||||||||||||||||||||||
| UIP | DAD | DAD | |||||||||||||||||||||||||||
| NSIP | NSIP | ||||||||||||||||||||||||||||
| DIP | DIP/RB | DIP | |||||||||||||||||||||||||||
| RB | |||||||||||||||||||||||||||||
| BIP | OP | OP | |||||||||||||||||||||||||||
| LIP | (LPD) | LIP | |||||||||||||||||||||||||||
| GIP | (HMF) | (HMF) | |||||||||||||||||||||||||||
UIP=usual interstitial pneumonia; DAD=diffuse alveolar damage; NSIP=non-specific interstitial pneumonia; DIP=desquamative interstitial pneumonia; RB=respiratory bronchiolitis; BIP=bronchiolitis obliterans interstitial pneumonia; OP=organizing pneumonia; LIP=lymphoid interstitial pneumonia; LPD=lymphoproliferative disease (not considered a diffuse lung disease); GIP=giant cell interstitial pneumonia; HMF=heavy metal fibrosis, no longer grouped with diffuse lung disease
Lymphoid interstitial pneumonia was originally included in this category, then excluded, then included again.
參考文獻
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||