Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.

群孕酮

Другие языки:

群孕酮

Подписчиков: 0, рейтинг: 0

**群孕酮**
臨床資料

商品名	Reteroid, Retroid, Retrone
其他名稱	Ro 4-8347; Triengestone; 1,6-Didehydro-6-chlororetroprogesterone; 6-Chloro-9β-10α-pregna-1,4,6-triene-3,20-dione
给药途径	By mouth
藥物類別	Progestin; Progestogen
ATC碼	None
法律規範狀態
法律規範	处方药（℞-only）
藥物動力學數據
生物利用度	≥41–46% (based on urinary excretion)
药物代谢	Liver
代謝產物	• 20α-Dihydrotrengestone
生物半衰期	• Trengestone: very short • 20α-DHTG: 8–14 hours
排泄途徑	Urine: 41–46% Feces: 30% (unchanged)
识别信息
IUPAC命名法 (8S,9S,10R,13S,14S,17S)-17-acetyl-6-chloro-10,13-dimethyl-8,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
CAS号	5192-84-7
PubChem CID	56840930
ChemSpider	28475379
UNII	VY6S496SVX
ChEBI	CHEBI:135458
ChEMBL	ChEMBL2107518
ECHA InfoCard	100.023.617
化学信息
化学式	C₂₁H₂₅ClO₂
摩尔质量	344.879 g/mol
3D模型（JSmol）	交互式图像
SMILES CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)C=C[C@]34C)Cl)C
InChI InChI=1S/C21H25ClO2/c1-12(23)15-4-5-16-14-11-19(22)18-10-13(24)6-8-21(18,3)17(14)7-9-20(15,16)2/h6,8,10-11,14-17H,4-5,7,9H2,1-3H3/t14-,15+,16-,17-,20+,21+/m0/s1 Key:USXVMPAWZOOYDE-HGUQNLGYSA-N

群孕酮（英語：Trengestone，商品名为Reteroid、Retroid或Retrone）是一种黄体制剂药物，曾经用于治疗月经失调，但现已不再使用

孕酮衍生物	孕酮奎孕酮

逆孕酮衍生物	地屈孕酮群孕酮

17α-羟孕酮衍生物 (and closely related)	Acetomepregenol (mepregenol diacetate) Algestone Algestone acetophenide Anagestone acetate Chlormadinone acetate 醋酸环丙孕酮 Delmadinone acetate Flugestone acetate (flurogestone acetate) Hydroxyprogesterone Hydroxyprogesterone acetate Hydroxyprogesterone caproate Hydroxyprogesterone heptanoate Medroxyprogesterone Medroxyprogesterone acetate^# Megestrol acetate Melengestrol acetate Osaterone acetate Pentagestrone acetate Other 17α-substitutions: Haloprogesterone Medrogestone Proligestone

19-去甲孕酮衍生物 (incl. 17α-substituted)	Demegestone Gestonorone caproate (gestronol hexanoate) Nomegestrol acetate Norgestomet Promegestone Segesterone acetate (nestorone) Trimegestone

17α-乙炔基睾酮衍生物	达那唑二甲炔酮炔孕酮

19-去甲睾酮衍生物	Estranes: Etynodiol diacetate 孕三烯酮 Lynestrenol 炔诺酮^# 醋酸炔诺酮庚酸炔诺酮异炔诺酮 Norgestrienone Quingestanol acetate 替勃龙性腺：去氧孕烯 Dienogest Etonogestrel Gestodene 左炔诺孕酮^# Norelgestromin Norgestimate Norgestrel 其他：Allylestrenol Altrenogest Norgesterone Normethandrone (methylestrenolone) Norvinisterone Oxendolone

17α-Spirolactosteroid	Canrenone Drospirenone Potassium canrenoate 螺内酯

其他	同化類固醇（如诺龙、诺龙酯、群勃龙、诺乙雄龙等等）