caBIG（cancer Biomedical Informatics Grid，癌症生物医学信息网格）是一个开放源码，可自由访问的系统，建立caBIG的目的是是使癌症研究人员之间有一个安全的数据交换信息网络。这一项目最初由美国国家癌症研究所（美国国立卫生研究院的一部分）倡议，并由其属下的生物医学信息学和信息技术中心（CBIIT）提供支持与维护。
项目起源
2004年美国国家癌症研究所（NCI）启动了caBIG（癌症生物医学信息网格）计划。该计划的目的是统合位于不同地方、从事癌症相关生物医药研究的各个部门的资源，从而使获得的数据类型多元化。该计划由生物信息学和信息技术中心（CBIIT）牵头，最初进行了3年的试运行，以测试其可行性。2007年3月试运行阶段结束。目前，在56个NCI的指定癌症中心进行着caBIG工具软件源码的的试验和应用。
对生物医学研究和个性化医疗的影响
医疗信息技术的应用
主要参与机构
项目实施情况
对开源事业的促进作用
批评意见
限制竞争
过度市场化
开发工具用途不明确
相关条目
参考资料
扩展阅读
- Abernethy AP, Coeytauz R, Rowe K, Wheeler JL, Lyerly HK. Electronic patient-reported data capture as the foundation of a learning health care system. JCO. 2009;27:6522.
- Buetow KH. caBIG: proof of concept for personalized cancer care. JCO. 2009:27 Suppl 15S:e20712.
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Holford ME, Rajeevan H, Zhao H, Kidd KK, Cheung KH. Semantic web-based integration of cancer pathways and allele frequency data. Cancer Informatics. 2009, 8: 19–30. PMC 2664696
. PMID 19458791.
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Huang T, Shenoy PJ, Sinha R, Graiser M, Bumpers KW, Flowers CR. Development of the Lymphoma Enterprise Architecture Database: A caBIG(tm) Silver level compliant System. Cancer Informatics. 2009, 8: 45–64. PMC 2675136 . PMID 19492074.
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Kunz I, Lin MC, Frey L. Metadata mapping and reuse in caBIG. BMC Bioinformatics. 2009,. 10 Suppl 2: S4. PMC 2646244 . PMID 19208192. doi:10.1186/1471-2105-10-S2-S4.
- Novik Y, Escalon L, Rolnitzky L. Academic cancer researchers' perspective on a federally mandated centralized comprehensive database of all cancer clinical trial results. JCO. 2009;27:e17576.
- Ohmann C, Kuchinke W. Future developments of medical informatics from the viewpoint of networked clinical research. Interoperability and integration. Methods of Information in Medicine. 2009, 48 (1): 45–54 [2011-03-14]. PMID 19151883. （原始内容存档于2013-02-11）.
- Phan JH, Moffitt RA, Stokes TH; et al. Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment. Trends in Biotechnology. June 2009, 27 (6): 350–8. PMID 19409634. doi:10.1016/j.tibtech.2009.02.010.
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Staes CJ, Xu W, LeFevre SD; et al. A case for using grid architecture for state public health informatics: the Utah perspective. BMC Medical Informatics and Decision Making. 2009, 9: 32. PMC 2707374 . PMID 19545428. doi:10.1186/1472-6947-9-32.
- Tan, Wei; Missier, Paolo; Madduri, Ravi; Foster, Ian. Building Scientific Workflow with Taverna and BPEL: A Comparative Study in caGrid: 118. 2009. doi:10.1007/978-3-642-01247-1_11.
- “Health IT gets personal,”（页面存档备份，存于互联网档案馆） InformationWeek (11/13/09)
- “Health data in the raw,”（页面存档备份，存于互联网档案馆） Government Health IT (11/6/09)
- “NCI to open research grid to cancer patient 'army',”（页面存档备份，存于互联网档案馆） Government Health IT (10/9/09)
- “GridBriefing: The future of Healthcare - eHealth and Grid Computing,”（页面存档备份，存于互联网档案馆） GridTalk (9/09)
- “Collaboration and Sustainability are Front and Center as caBIG Celebrates Fifth Anniversary,”（页面存档备份，存于互联网档案馆） GenomeWeb/BioInform (7/09)
- “Love/Avon Army of Women to Use NCI's caBIG Computational Platform for Breast Cancer Research,”（页面存档备份，存于互联网档案馆） The Scientist (7/09)
- “Sharing the Wealth of Data,” Scientific American (5/09)
- “Translational Research Drives Demand for 'Virtual' Biobanks Built on caBIG Tools,”（页面存档备份，存于互联网档案馆） GenomeWeb/BioInfom (4/3/09)
- “Connecting the Cancer Community caBIG Time,”（页面存档备份，存于互联网档案馆） Bio-IT World (7/14/08)
- “Heading for the BIG Time,” The Scientist (4/08)
